Victor Ambros of UMASS Medical Named Co-Recipient of 2014 Gruber Genetics Prize
Thursday, June 19, 2014
Ambros will share the award with collaborators Gary Ruvkun, PhD, professor of genetics at Massachusetts General Hospital and Harvard Medical School, and David Baulcombe, PhD, professor of botany at the University of Cambridge.
MicroRNAs and interfering RNAs
Ambros, Ruvkun, and Baulcombe were recognized for their discoveries of the existence and function of microRNAs and small interfering RNAs. These molecules play a critical role in gene expression.
“The discoveries of these three pioneering scientists have opened major new areas in chemistry, biology, agriculture and medicine, and have revealed fundamental mechanisms that are shared among organisms as diverse as plants and animals, including humans,” said H. Robert Horvitz, PhD, Gruber and Nobel Prize laureate, and David H. Koch Professor at the Massachusetts Institute of Technology (MIT).
miRNAs have been implicated in a range of both normal and pathological activities including embryonic development, blood-cell specialization, muscle function, heart disease and viral infections.
“At one time, these small RNAs were considered just an unimportant scientific oddity,” says Huda Y. Zoghbi, MD, professor of molecular and human genetics at Baylor University and chair of the selection advisory board to the Gruber Prize. “But thanks to the exciting work of Victor Ambros, Gary Ruvkun and David Baulcombe, we now know that they are anything but unimportant, both to human health and to the health of the planet.”
Gruber Genetics Prize
The Gruber Genetics Prize, established in 2001, is awarded for fundamental insights in the field of genetics and may include original discoveries in genetic function, regulation, transmission and variation, and genomic organization.
The prize, which is awarded along with a gold medal and an unrestricted $500,000 cash award, will be presented to the recipients in San Diego on Oct. 19 at the annual meeting of the American Society of Human Genetics.
Ambros is the Silverman Chair in Natural Sciences and co-director of the RNA Therapeutics Institute. His research includes microRNA function and gene regulation during development as well as the genetic and molecular mechanisms that control cell division, differentiation and morphogenesis in animals.
Related Slideshow: 13 Biggest Healthcare Stories in Central MA in 2013
The most import stories from one of the most historic years in memory for Central Massachusetts healthcare.
13 Inspection Scores
INTERACTIVE: Worcester Restaurant Health Inspection Tracker
Before you go out to dinner, make sure you know about the cleanliness of the establishment. GoLocalWorcester spent weeks going through the files of every health inspection in Worcester for nearly 700 restaurants. Use our proprietary interactive map to check any restaurant before you go out to eat. Check out our interactive map and fully sortable and rankable tabular data set to explore how your favorite restaurants did on their latest health inspections.
GoLocal also reported on the 50 Restaurants with the Worst Health Code Scores in Worcester and talked with experts about inspections -- and foodborne illnesses.
12 MA's Top 25 Diseases
The 25 Biggest Diseases To Strike Massachusetts
What infectious diseases hit Massachusetts the hardest, and in the biggest numbers? In July, The Centers for Disease Control (CDC) released its latest data for "notifiable diseases," defined as those infectious diseases "for which regular, frequent, and timely information regarding individual cases is considered necessary for the prevention and control fo the disease," according to the CDC. The latest data reports the number of cases in MA from 2011.
11 Famous Twins Thriving
Worcester Twins Thriving 17 Years After Famous Hug
When the Jackson twins were born 12 weeks premature in October of 1995 in Worcester, doctors were not sure if the two newborn girls were going to make it.
When one started to fade at just three weeks old, a nurse thought to put her sister in the same incubator as her, resulting in an immediate improvement in her health and the famous photograph of the "rescuing hug."
Now the girls are thriving 17-year-olds, and their story was recently featured on CNN.
10 High Stress in MA
Gallup Poll: MA 5th Most Stressed Out State
A new poll from Gallup revealed that Bay State residents are a bunch of worrywarts. According to their most recent ranking, Massachusetts is facing the fifth highest levels of stress in the country.
While the Commonwealth’s ranking in this Gallup poll didn’t change since last year (also fifth place), the figures did shift.
9 Healthiest Counties
The Healthiest Counties in Massachusetts
Worcester County ranked 9 out of Massachusetts’ 14 counties in overall health according to 2013 rankings by the Robert Wood Johnson Foundation, a national foundation focused on improving public health. The 2013 County Health Rankings place Worcester County somewhere near the bottom of pack. Dukes and Middlesex counties are the healthiest, while Suffolk and Hampden counties are the least healthy.
8 MA Sexual Health
New National Ranking: How Sexually Healthy Is MA?
Massachusetts came in 4th place for sexual health in New England, according to the brand-new Sexual Health Rankings, just released this week.
The first-ever assessment of state-by-state data on 26 comprehensive health and services measures that speak to sexual health put the Bay State at #5 overall in the US, and #4 among New England states. Vermont was the #1 state in the country for sexual health, while Mississipi was the worst at #51. Variance, LLC, has produced the rankings in collaboration with The Center for Sexual Pleasure and Health, an education and advocacy organization based in Pawtucket, RI.
7 Health Code Experts
Experts Weigh in on Restaurant Inspections and Foodborne Illness
While restaurant inspections are required throughout the country, how they are conducted, recorded, and utilized varies greatly among towns and cities. While our custom interactive let you explore the inspections, its improtant to temper and contextualize your discoveries (some of them surprising!) with input from chefs, doctors, and national experts.
We reached out to a wide array of each when we conducted our look into the worst health inspection offenders in Worcester.
6 Rampant Opioid Abuse
Massachusetts Drug Overdose Deaths Up 47% Since 1999
Last year we reported that Worcester's heroin use was twice the national average - Massachusetts is the top state in the country for opioid overdoses, and lifetime heroin use in Worcester is almost 5%, twice the state and national average.
This year a report recently released by the Trust for America’s Health (TFAH) showed that overall drug overdose deaths in Massachusetts have climbed 47% since 1999. The Bay State is now ranked 32nd out of 50 states in annual drug overdose deaths, with nearly 11 of every 100,000 deaths resulting from an overdose. The majority of these deaths were the result of prescription drug abuse- opioids.
5 Curbing Candy Craze
11 Ways To Help Kids Curb Their Halloween Candy Craze
This Halloween, while Central Massachusetts kids were gearing up for a candy extravaganza, their parents were dreading the sugar assault on their children's health.
Statistics that show that Americans buy nearly 600 million pounds of candy during the Halloween season. That boils down to about 1.9 pounds of candy per person.
Kate Roberts, a consulting psychologist to school districts throughout Rhode Island and Massachusetts, says that with obesity and diabetes on the rise, not to mention the scare you’ll get at the dentist’s office parents may want to limit some of this devilish behavior.
4 Sale of St. Vincent's
Controversy Surrounds Buyer of St. Vincent + MetroWest Hospitals
On June 24th, Major US hospital operator Tenet Healthcare Corporaton announced its intention today to buy Vanguard Health Systems Inc for $1.73 billion, a purchase that would include Worcester's St. Vincent Hospital. The purchased marked the re-entry of Tenet Healthcare, a familiar and legally challenged for-profit hospital chain, back to Central Massachusetts.
Tenet owned the Central Mass. hospital once before, selling it to Vanguard in 2004. At the time, Tenet faced federal charges of Medicaid fraud. It wasn’t the first time that would happen, and it wouldn’t be the last. In the past decade, Tenet has shelled out more than $1 billion to settle a laundry list of legal charges. Read on to learn about the charges and for expert commentary on what their re-entry means for St. Vincent's and its patients.
3 Nursing Home Rankings
Massachusetts Ranked #19 on National Nursing Homes Report Card
Massachusetts received a "B" ranking for nursing home quality of care from "Families for Better Care," a national nursing home resident advocacy group -- and earned the #19 top spot in the country overall.
The group published the nation’s "first-ever state-by-state nursing home report card" by analyzing eight federal measures to rank nursing home quality.
But local experts warned that MA's ranking did not directly mirror the more local picture in Worcester. While roughly 2/3 of nursing home residents in Massachusetts are there under Medicaid programs, the number is closer to 3/4 in Worcester County, according to Ernie Corrigan with the Massachusetts Senior Care Association. So do some more local research- check out our complete ranking and ensure the nursing homes you choose are not among the 1/3 of Worcester nursing homes graded "below average".
2 Nurses Fight at UMass
UMass Memorial Nurses Vote to Strike
Staff members at UMass Memorial hospital were embroiledinvolved in heated talks with the hospital’s administration, with the Massachusetts Nurses Association (MNA) union at their side. 2,000 of the hospital’s nurses were ready to take it to the next level. The nurses alleged that they were under staffed and putting patients at risk. The standoff dated back to mid-2012 and culminated around midnight on May 23rd, the night before the one-day strike was set to begin when a deal was reached to avert the strike.
November 15, 2012: UMass Memorial and Nurses Union Clash Over “Dangerous Mismangement”
December 13, 2012: Nurses Picket UMass Memorial Over Staffing + Pension Cuts
February 23, 2013: Local Nurses Say Hospitals “Skirting the Law”
April 11, 2013: UMass Memorial Nurses Prepared to Strike
April 12, 2013: UMass Memorial Nurses Vote to Strike
May 10, 2013: UMass Memorial Nurses to Hold One-Day Strike
May 20, 2013: UMass Memorial Univ. Campus Nurses Strike Still Looming
May 23, 2013: No Strike—UMass Memorial and Nurses Reach Agreement
1 Patients Rank Hospitals
New England’s Best Hospitals Rated By Patients
Traditionally, hospitals are rated and ranked on a combination of sound technical care, adequate resources, and impressive statistics. But an increasing emphasis is being placed on perhaps one of the more important measures: the patient’s perspective. With that in mind, GoLocal has sifted through and analyzed the results from a government-sponsored survey of more than 50,000 patients in 176 hospitals in New England (full chart here), and emerged with the first-ever patient-based ranking of the region’s top hospitals.
GoLocal consulted with patients, experts, and hospital administrators for their take to contextualize the rankings- click here to read the story.
- UMass Medical School Doctor Named to TIME’s Top 100
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- UMass Med School Faculty Recognized as a Top Young Scientist in US
- WPI + UMass Medical Team Discover Breakthrough in Deadly Infection